/Users/andrea/_magisterarbeit/korpus/clean/trainkorpus/31/file3.html NN ----------------------------------------- : Management NP Team NP Board NP of IN Directors NPS home NN About IN Us NP About IN Us NP Lexicon NN Genetics NP is VBZ a DT biopharmaceutical JJ company NN focused VVN on IN the DT discovery NN of IN breakthrough NN treatments NNS for IN human JJ disease NN . SENT We PP are VBP systematically RB discovering VVG the DT physiological JJ and CC behavioral JJ functions NNS of IN genes NNS to TO identify VV potential JJ points NNS of IN therapeutic JJ intervention NN , , or CC drug NN targets NNS . SENT We PP make VVP these DT discoveries NNS using VVG our PP$ proprietary JJ technology NN to TO knock VV out RP , , or CC disrupt VV , , the DT function NN of IN genes NNS in IN mice NNS . SENT Our PP$ gene NN knockout NN technology NN allows VVZ us PP to TO model NN , , on IN a DT genome NN wide JJ scale NN , , the DT effects NNS on IN physiology NN that WDT could MD be VB expected VVN from IN prospective JJ drugs NNS directed VVN against IN novel NN targets NNS . SENT For IN targets NNS that IN we PP believe VVP have VH high JJ pharmaceutical JJ value NN , , we PP engage VVP in IN programs NNS for IN the DT discovery NN and CC development NN of IN small JJ molecule NN drugs NNS , , therapeutic JJ antibodies NNS and CC therapeutic JJ proteins NNS . SENT We PP have VHP advanced VVD more JJR than IN 70 CD knockout NN validated VVD targets NNS into IN drug NN discovery NN programs NNS in IN six CD therapeutic JJ areas NNS . SENT diabetes NN and CC obesity NN , , cardiovascular JJ disease NN , , psychiatric JJ and CC neurological JJ disorders NNS , , cancer NN , , immune JJ system NN disorders NNS and CC ophthalmic JJ disease NN . SENT Our PP$ physiology NN based VVN approach NN to TO understanding VVG gene NN function NN and CC our PP$ use NN of IN knockouts NNS to TO model VV expected VVN drug NN action NN are VBP designed VVN to TO identify VV new JJ ways NNS to TO treat VV major JJ human JJ diseases NNS . SENT We PP are VBP using VVG our PP$ proprietary JJ gene NN knockout NN technology NN in IN our PP$ Genome NN 5000 CD program NN to TO rapidly RB discover VV the DT functions NNS of IN the DT most RBS pharmaceutically RB important JJ genes NNS in IN the DT human JJ genome NN 5 CD , , 000 CD genes NNS that WDT have VHP desirable JJ characteristics NNS for IN pharmaceutical JJ development NN . SENT To TO date VV , , we PP have VHP completed VVN our PP$ analysis NN of IN more JJR than IN one CD third NN of IN these DT genes NNS . SENT We PP believe VVP our PP$ unique JJ ability NN to TO systematically RB determine VV the DT physiological JJ and CC behavioral JJ function NN of IN genes NNS provides VVZ us PP with IN a DT strategic JJ advantage NN in IN the DT race NN to TO discover VV future JJ breakthrough NN therapeutics NNS . SENT We PP are VBP working VVG both CC independently RB and CC through IN strategic JJ collaborations NNS and CC alliances NNS to TO accelerate VV the DT development NN and CC commercialization NN of IN our PP$ discoveries NNS . SENT We PP have VHP formed VVN a DT broad JJ alliance NN with IN Bristol NP Myers NP Squibb NP for IN drug NN discovery NN , , development NN and CC commercialization NN in IN the DT neuroscience NN field NN . SENT We PP are VBP working VVG with IN Genentech NP , , Inc NP . SENT to TO discover VV the DT functions NNS of IN secreted VVN proteins NNS and CC potential JJ antibody NN targets NNS identified VVN through IN Genentech's NP internal JJ drug NN discovery NN research NN . SENT We PP are VBP collaborating VVG with IN Organon NN to TO jointly RB discover VV , , develop VV and CC commercialize VV novel NN biotherapeutics NN . SENT We PP have VHP established VVN an DT alliance NN with IN Takeda NP Pharmaceutical NP Company NP Limited NP to TO accelerate VV the DT development NN and CC commercialization NN of IN new JJ drugs NNS for IN the DT treatment NN of IN high JJ blood NN pressure NN . SENT We PP have VHP also RB established VVN numerous JJ other JJ collaborations NNS with IN leading VVG pharmaceutical JJ and CC biotechnology NN companies NNS , , as RB well RB as IN research NN and CC academic JJ institutions NNS . SENT back RB to TO top VV Contact NP Us NP Terms NNS of IN Use NN Site NN Map NN Search NP Home NP Copyright NP 2005 CD , , Lexicon NN Genetics NP Incorporated VVD . SENT All DT rights NNS reserved VVD . SENT